Researchers warn covid-19 could cause debilitating long-term illness in some patientsIn the fall of 2009, one of us, Beth, was hit by an illness she suspects was H1N1 flu, which was circulating then. In 2012, the other, Brian, developed a sudden fever, which his doctors said was also likely of viral origin. Neither of us recovered, and we're both disabled to this day. The long-term illnesses that can follow viral infections can be devastating - and are devastatingly common. In 2015, the nation's top medical advisory body, the Institute of Medicine, estimated that between 800,000 and 2.5 million U.S. residents live with the illness or illnesses awkwardly named myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). An estimated three-quarters of these cases were triggered by viral or bacterial infections. Now, as a new pandemic virus is burning through the world and causing many deaths, researchers are raising alarms that the novel coronavirus and the covid-19 disease it causes will also leave in its wake a potentially large population with post-viral problems that could be lifelong and, in some cases, disabling. At the National Institutes of Health and elsewhere, scientists who have been studying post-viral ME/CFS are seizing the opportunity to focus on covid-19 patients. They want to understand what biological factors separate those who regain their health from those who remain sick. "We want to look at who recovers and who doesn't," said Avindra Nath, the head of clinical neurology at NIH's Clinical Center in Bethesda, Maryland, who is gearing up to study covid-19 patients. "It's quite possible some will never get their health back." In addition to emerging reports of damage to lungs, kidneys and hearts, covid-19 patients are complaining of ongoing crushing fatigue, muscle pain, cognitive problems and other symptoms that anyone with ME/CFS is...
International community rallies to support open research and science to fight COVID-19WHO and Costa Rica launch landmark COVID-19 Technology Access PoolThirty countries and multiple international partners and institutions have signed up to support the COVID-19 Technology Access Pool (C-TAP) an initiative aimed at making vaccines, tests, treatments and other health technologies to fight COVID-19 accessible to all.The Pool was first proposed in March by President Carlos Alvarado of Costa Rica, who joined WHO Director-General Dr Tedros Adhanom Ghebreyesus today at the official launch of the initiative. “The COVID-19 Technology Access Pool will ensure the latest and best science benefits all of humanity,” said President Alvarado of Costa Rica. “Vaccines, tests, diagnostics, treatments and other key tools in the coronavirus response must be made universally available as global public goods”. “Global solidarity and collaboration are essential to overcoming COVID-19,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “Based on strong science and open collaboration, this information-sharing platform will help provide equitable access to life-saving technologies around the world.” The COVID-19 (Technology) Access Pool will be voluntary and based on social solidarity. It will provide a one-stop shop for scientific knowledge, data and intellectual property to be shared equitably by the global community. The aim is to accelerate the discovery of vaccines, medicines and other technologies through open-science research, and to fast-track product development by mobilizing additional manufacturing capacity. This will help ensure faster and more equitable access to existing and new COVID-19 health products. There are five key elements to the initiative:Public disclosure of gene sequences and data;Transparency around the publication of all clinical trial results;Governments and other funders are encouraged to include clauses in funding agreements with pharmaceutical companies and other innovators about equitable distribution, affordability and the publication of trial data;Licensing any potential treatment, diagnostic, vaccine or other health technology to the Medicines Patent Pool - a United Nations-backed public health body that works to increase access to, and facilitate the development of, life-saving medicines for low- and middle-income countries.Promotion of open innovation models and technology transfer that increase local manufacturing and supply capacity, including through joining the Open Covid Pledge and the Technology Access Partnership (TAP).With supportive countries across the globe, C-TAP will serve as a sister initiative to the Access to COVID-19 Tools (ACT) Accelerator and other initiatives to support efforts to fight COVID-19 worldwide.WHO, Costa Rica and all the co-sponsor countries have also issued a “Solidarity Call to Action” asking relevant stakeholders to join and support the initiative, with recommended actions for key groups, such as governments, research and development funders, researchers, industry and civil society.WHO and Costa Rica co-hosted today’s launch event, which began with a high-level session addressed by the WHO Director-General and President Alvarado in addition to Prime Minister Mia Mottley of Barbados and Aksel Jacobsen, State Secretary, Norway. There were video statements by President Lenín Moreno of Ecuador; President Thomas Esang Remengesau Jr., of Palau; President Lenín Moreno of Ecuador; , Michelle Bachelet, United Nations High Commissioner for Human Rights; Jagan Chapagain, Secretary General of the International Federation of Red Cross and Red Crescent Societies; and Retno Marsudi, Minister for Foreign Affairs for Indonesia. Leaders from across the UN, academia, industry and civil society joined for a moderated discussion.To date, the COVID-19 Technology Access Pool is now supported by the following countries: Argentina, Bangladesh, Barbados, Belgium, Belize, Bhutan, Brazil, Chile, Dominican Republic, Ecuador, Egypt, El Salvador, Honduras, Indonesia, Lebanon, Luxembourg, Malaysia, Maldives, Mexico, Mozambique, Norway, Oman, Pakistan, Palau, Panama, Peru, Portugal, Saint Vincent and Grenadines, South Africa, Sri Lanka,Sudan, The Netherlands, Timor-Leste, Uruguay, ZimbabweOther international organizations, partners and experts have also expressed support to the initiative and others can join them using the website.Note to Editors:The Solidarity Call to Action follows from numerous international commitments, including: Global Sustainable Development Goal 3, target 3b; The WHO Global Strategy and Plan of Action on Public Health, Innovation and Intellectual Property (GSPA- PHI) and the WHO Roadmap for access to medicines, vaccines and health products 2019-2023; the UN General Assembly Resolution on “International cooperation to ensure global access to medicines, vaccines and medical equipment to face COVID-19” (A/RES/74/274); and the 73rd World Health Assembly Resolution on the “COVID-19 response” (WHA73.1).To access the event: https://who.zoom.us/j/99683467690 - Password: WHO%OMS27
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